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Origin of biomolecular Asymmetry

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Daily Telegraph London 10.4.2002



View from the lab

Alcohol in space? Take more ice with it
recommends Prof Steve Jones

ON an American plane I was once given a bottle of fizzy
water that bore the caution: "Small crystals may appear
in this liquid in cold conditions. These are of no danger to
health and will disappear upon warming," a statement
reminiscent of the bag of peanuts that is supposed to
have said "This product may contain nuts".

Such admonitions sound absurd (although, given the real
dangers of peanut allergy, the second is not as silly as it
seems). The famous crystals are, of course, ice, and to
those of us who prefer our airborne H2 O in that form
because it dilutes the other liquid we have just poured
into the glass would be better served by a health warning
on the gin miniature (as found on those sold in America).

But ice is less simple than it seems. Cool water down
slowly in a domestic freezer and it may stay liquid - until
you give the container a sharp tap and the whole lot
suddenly goes hard. To move from one phase to another
- from disorder to order, liquid to solid, water to ice -
takes energy. Once a few molecules have been forced
together (a sudden blow helps) the great shift of state
happens at once, as it spreads from a single point.

A speck of dust (banned, no doubt, from bottled water) is
also a great aid in persuading reluctant molecules to get
together. It acts as a local nucleus to which they can
attach themselves. That reduces the endless vibration
intrinsic to the liquid state, allows them to overcome their
natural disinclination to join and sparks off the big freeze.

Now comes news that, far above the heads of even the
determined tipplers of Business Class, life itself may have
started as an airborne, albeit dusty, gin and tonic.

Space is like a great cathedral - a large, cold, empty and
sometimes rather grimy place. Stardust, now and again,
forms solar systems (our own included) but, most of the
time, it is just dust. Just as on Earth, it acts as a centre of
attraction for the other chemicals that float in minute
quantities through the heavens. Without such crucial
meeting places in the almost vacant universe, they would
scarcely ever come into contact, but upon the tiny
particles - just as in a bottle of chilled water - the
molecules of the great void can get together and freeze.

As a result, the grains are covered with ice and solid
carbon dioxide. They can also bear other unexpected
elements of the interstellar cocktail. Certain corners of
the Universe serve up copious quantities of alcohol. One
single star in the Aquila galaxy, 10,000 light years from
home, has a cloud of ethyl alcohol around it big enough
for a bottle of the finest Gordon's for every person on
Earth, every day for the next five thousand billion years.

Some new, Earth-bound experiments hint at a strange
chemistry that may happen within that great astronomical
brew. In the icy cold of a Dutch laboratory, a quick blast
of ultraviolet light of the sort given out by the Sun on to
an artificial version of the icy and alcoholic stardust (plus,
alas, a dash of ammonia: an ingredient absent from any
beverage I have ever tried) and - hey presto - some
unexpected substances appear.

They are amino acids, the building blocks of life itself.
Some are identical to those found in our own bodies. If
polarised UV, whose waves vibrate in only one plane, is
used in the experiment, then the new molecules are
twisted to one side, as is the case for our own amino
acids, but not for those made by ordinary chemistry
(which gives a mixture of the two mirror-image forms).
Some of the dustiest parts of the sky do emit polarised
ultraviolet, which may explain why the building blocks of
life on Earth lean so much in one direction (the left, as it
happens).

Lab experiments that try to mimic the chemistry of space
inevitably involve a certain guesswork. Nasa's Stardust
probe is now flying through great clouds of tiny particles
at the edge of the solar system and collecting them in a
special net. When it gets back to Earth in 2006 we may
find out just what they are made of and whether freshly
made versions of our body chemicals are indeed floating
through the void.

To claim that astral amino acids actually prove that life
began out there is no more convincing than to use the
discovery of marble on some distant planet as evidence
that the Parthenon was built by aliens. Even so, the
thought surely deserves contemplation over another glass
of something fizzy as the flecks of dust left after the Big
Bang rain gently down outside.

Steve Jones is professor of genetics at University
College London


Last updated April 2002